PPARgamma activators stimulate aquaporin 3 expression in keratinocytes/epidermis
نویسندگان
چکیده
منابع مشابه
Inhibition of MMP-9 expression by PPARgamma activators in human bronchial epithelial cells.
BACKGROUND The release of matrix degrading enzymes such as matrix metalloproteinase 9 (MMP-9) from bronchial epithelial cells is critically involved in airway wall remodelling in chronic inflammatory processes of the respiratory system. MMP-9 expression is induced by inflammatory mediators such as tumour necrosis factor (TNF)-alpha, but to date nothing is known about the mechanisms of inhibitio...
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To explore the possible mechanism of the third-generation retinoic acid drugs (isotretinoin, acitretin, adapalene) in inducing skin and mucosa dryness and rhagades; specifically, mechanism by which these drugs influence keratinocyte cell culture models in vitro (HaCaT) and aquaporin channel (AQP3) protein expression was investigated. Isotretinoin, acitretin, and adapalene were applied to human ...
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ژورنال
عنوان ژورنال: Experimental Dermatology
سال: 2011
ISSN: 0906-6705
DOI: 10.1111/j.1600-0625.2011.01269.x